Ceftriaxone-AFT contains the active ingredient ceftriaxone sodium. Ceftriaxone-AFT is an antibiotic used to treat infections in different parts of the body caused by bacteria. Ceftriaxone-AFT is also used to prevent infections before, during and after surgery. It will not work against infections caused by viruses such as colds and flus. Ceftriaxone-AFT belongs to a group of antibiotics called cephalosporins. They work by killing the bacteria that are causing your infection or by stopping the bacteria from growing.